Its usage and effect have been described in these words: "Repaglinide is commonly used in people with type 2 (non-insulin-dependent) diabetes. It is administered alone or with other medications to control high blood sugar levels, together with a proper diet and exercise program ... This medication works by lowering blood glucose by stimulating the release of insulin from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the beta cells. This depolarizes the beta cells, opening the cells' calcium channels, and the resulting calcium influx induces insulin secretion."